Calculated from the hazard ratios of ischemic cardiovascular disease (cerebral infarction, myocardial infarction, angina pectoris, and acute coronary death) at during the median15 year-followup of participants aged 40-74 (Circulation Risk in Communities Study: CIRCS).

Reference: Yamagishi K, et al. J Epidemiol. 2019;29(3):83-91.
doi:10.2188/jea.JE20180196

Calculation was based on the method by Sullivan, Lisa M et al. Statistics in medicine vol. 23,10 (2004): 1631-60. doi:10.1002/sim.1742